Genomics

Robust analysis of allele-specific copy number alterations from scRNA-seq data with XClone

XClone is an algorithm to infer allele- and haplotype-specific copy numbers in individual cells from low-coverage and sparse single-cell RNA sequencing data (e.g., those generated by 10x Genomics, Smart-seq, etc.)

MQuad enables clonal substructure discovery using single cell mitochondrial variants

MQuad: Mixture Model for Mitochondrial Mutation detection in single-cell omics data